This study was conducted to figure out the impacts of utilizing technology-based method in comparison to Grammar Translation Method (GTM) of teaching aviation vocabulary to Iranian upper-intermediate EFL pilots. The study involved 49 upper-intermediate Iranian EFL student pilots, divided into experimental (24 participants) and control (25 participants) groups. The experimental group utilized XCLASS software as their e-learning platform, which enabled students to listen to aviation audio files through headphones and share Word files via computers in teacher-designated groups and pairs, while the control group received instruction through the Grammar Translation Method. Data collection involved a pretest, followed by 14 instructional sessions for both groups, and concluded with a posttest. Analysis through independent-sample t-test (t(58) = 3.57, p = .001, p < .01) revealed that e-learning practices demonstrated superior effectiveness compared to traditional GTM in developing aviation vocabulary knowledge among Iranian upper-intermediate EFL pilots. These findings suggest that pilot language schools and institutions should prioritize e-learning practices, and educational policies should incorporate technology-enhanced teaching methodologies.